The game is pretty prone to crashing, if you're running the game at any higher than 1080p it will crash. This might be the case with multimonitor setups as well. If you're running at higher than 1080p try using the windowmode plugin, but if your not it could be because of a few things, all.pkr not extracted and dummied, or ddraw/dinput/other dlls missing/unpatched. it could also be because directplay isn't installed which isnt included with windows anymore, you can go to the add and remove features panel and install it. If none of these work I have a preinstalled copy of the game that just works when copying across machines, I'm working on making an installer package for the game with everything preapplied